If you think it is all OEM, bypass the breaker with the same rating fuse in a holder and give it the everything on test.  If it doesn't blow, consider replacing the breaker.

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Thanks for all of the info. Is there a chance it's also a simple calibration issue? The shop I used said that shouldn't affect it but I'd have to imagine since there's a calibration button it's worth a shot.

My 2010 Malibu LSV20 is generating “Trans over temp” alerts that appear to be false alarms, as the trans is not heating up and seems to be working fine. We replaced the sensor on the top of the trans and still get the alert. We then disconnected the sensor altogether, and we STILL get the alert. 
 

Anyone have any ideas, and/or a wiring diagram for this boat so we can try to track down or isolate?  At this time, we believe the problem might be in the wiring between the connector to the sensor and the dashboard display, as the wires coming out of the connector to the sensor seem to be routed to the throttle control box and not to the ECU. 

Any ideas help (. Or wiring diagrams) are appreciated. 

There are two screw terminals on the power module under the helm labeled power wedge (black) with a black wire, and power wedge (white) with a white wire (see previous photo).  You can switch those wires to make the power wedge move opposite of the way you are controlling it with the MUX.  Using a voltmeter to test the voltage and ground on those terminals when running the wedge up or down can also help determine what the problem may be. 

Please don't overlook the other suggestions.  The most common issues I've seen after actuator replacement is loose electrical connections, the wedge wing binding, or the power wedge adjustment bracket not being properly adjusted for the actuators.